our p b p n blog.
this is : liveric.blogspot.com
A blog set up for the subject
Principles of Biochemistry & Physiology for Nutrition (PBPN)
by students of A7A1
just for Mdm Kalpana!:D
Our Question:
Our immune system tends to mount an immune response to the entry of an antigen from the same species (e.g. renal transplant).
- Discuss on the factors to be considered to prevent renal transplant rejection.
- Artificial implants (like pace makers, knee/hip joints?) and corneal transplants are not rejected by our immune system? Why?
Topic of Discussion:
* What is Immune System and How Does It Work?
* Renal Transplant Rejection
* Artificial implants and Corneal Transplants
* Q&A Session
* Interesting Facts!!
* Glossary
navigations are on top.=)
Sunday, February 8, 2009
Topic:
Artificial implants and Corneal Transplants
Artificial implants such as pace makers and knee/hip joints are usually made of titanium, and is inert in the body. Since MHC is not present on the surface of the implants, our immune system regard these artificial implants as their own and does not try to attack them.
Corneal transplant are not usually rejected by our body’s immune system as it is a type of special collagen and has no blood vessels. Antigens that causes immune response in our bodies has to be in contact with blood vessels. Since there are no blood vessels, leukocytes are not able to attack the transplanted cornea. This is the reason why most of the cornea transplantations are performed successfully.
References
1. www.zampbioworld.org (2009) Prevention Of Organ Rejection In Stable Kidney Transplant Patients - LCP-Tacro™ Moves Into Clinical Phase 3. Retrieved February 1, 2009, from http://www.zampbioworld.org/bionews/index.php/2009/01/02/13684
2. AbsoluteAstronomy.com (2009) Artificial Pacemaker. Retrieved February 1, 2009, from http://www.absoluteastronomy.com/topics/Artificial_pacemaker
3.Advameg Inc. (2007) Corneal Transplantation. Retrieved February 1, 2009, from http://www.surgeryencyclopedia.com/Ce-Fi/Corneal-Transplantation.html